Hair loss in men is attributed to one main culprit!
The scene of the crime: When the male hormone testosterone reacts with the excessively-active 5α-Reductase enzymes, the result is the production of the ‘killer’ of hair follicles – Dihydrotestosterone (DHT). An overbalanced amount of DHT will begin to attack hair follicles, resulting in their shrinkage and causing hair thinning and hair loss. Eventually, chronic hair loss will contribute to the death of hair follicles, halting the growth of new hair and inducing a phenomenon that is commonly experienced by men — androgenetic alopecia, or male-pattern baldness. As 5α-Reductase is secreted from the hair follicles on the hairline or the crown of the head, a common sign of male-pattern baldness is the M-shaped hairline or the Mediterranean Sea pattern, whilst hair on the back of the head remains unaffected.
So that’s it! 5α-Reductase is the ultimate culprit of male-pattern baldness. In order to reduce hair loss, it is important to control the level of 5α-Reductase activity and reduce the concentration of DHT.